With the era of the DMAA-based Jack3d drawing to a close, Jack3d manufacturers hope customers turn to Jack3d Advanced Formula.
Jack3d Advanced Formula doesn’t include the 1,3-DMAA, which was banned. Anticipation is growing for what could be another great pre-workout supplement.
I decided to look closer at the ingredients.
Who Makes Jack3d Advanced Formula?
The Jack3d line—including Jack3d Advanced Formula—is manufactured and sold by the Texas-based supplement company USPLabs.
USPLabs has been in business since 2006 and currently has an A+ rating with the Better Business Bureau. USPLabs is also BBB accredited, which means the company has made a commitment to resolve any customer complaints filed with the BBB.
In the past 3 years, only 3 complaints have been filed against USPLabs. All have been resolved.
I like finding companies that have been in business for a while and have a good track record. This lets customers know the business leaders operate honestly.
So, together with an impressive performance track record, USPLabs’ business reputation makes me take Jack3d Advanced Formula more seriously than I would otherwise, judging by Jack3d Micro’s failure to impress.
What Are the Ingredients?
The ingredients in Jack3d Advanced Formula are listed in a proprietary blend. Specific doses for each ingredient are not know, so it is hard to tell if ingredient amounts are equal to supporting clinical studies.
Arginine nitrate optimizes blood flow. 
Arginine nitrate, additionally, yields more nitric oxide by utilizing a nitrate-nitrite-nitric oxide pathway. 
Advanced Creatine Ratio (Monohydrate, Anhydrous)
Creatine, composed of amino acids, supplies extra by offering an extra phosphate molecule to optimize ATP production. Increased ATP results in extra fuel for muscle contractions, enhancing athletic performance and workouts.
In one study, college volleyball players were given 5 g creatine a day as they trained 3 times a week. Due to the creatine supplementation, the athletes were able to bench press more and also experienced increases in vertical jump measurements. 
The company also claims creatine anhydrous is even more pure than monohydrate (highly bioavailable). Unfortunately, I could not find evidence supporting this claim.
Yohimbe increases blood flow.  Yohimbe research is extremely limited however, and most research surrounding yohimbe is related to aiding sexual impotence due to its ability to enhance blood flow.
Caffeine (100 mg)
Caffeine is a stimulant often times used in work out supplements because it is known to increase strength during resistance exercise.
Athletes, in one study, consumed 5 mg/kg caffeine before doing chest press exercises. This caffeine supplementation resulted resulted in more weight lifted. 
There should be enough caffeine in Jack3d Advanced Formula to offer similar results.
Pinus Pinaster (Bark) Extract
Pinus pinaster relieves muscle cramps.
In one study, 200 mg pinus pinaster doses and 1.5 liters of water were given to 66 test subjects daily. Researchers studied muscle cramp episodes during the study and discovered the test subjects experienced less muscle cramps than usual. 
Beta Alanine (Carnosyn)
Beta alanine contributes to carnosine synthesis which is important because carnosine combats muscle fatigue.
One study shows athletes given 6 g beta alanine a day experienced enhanced physical performance due to higher carnosine levels which delayed lactic acid formulation. 
Little is known about Jack3d Advanced Formula, especially because there are little to no user reviews. Though, side effects associated with ingredients in Jack3d Advanced Formula are low blood pressure, bloating, diarrhea, nausea, kidney failure, heart attack, restlessness, and abdominal pain.    
The label reads: “Mix 1 Ultra-Concentrated Scoop (5.1 grams) with 4 ounces of cold water and consume 30-45 minutes prior to resistance training. Do this the first 3 times using the product. Beginning with the 4th use, if needed, you may gradually increase serving by a half scoop (2.55 grams), up to a total of 2 full scoops.”
Additionally, the manufacturer warns users not exceed 2 full scoops in a 24 hour period or use more than 5 days in a 7 day period. The manufacturer also recommends drinking at least 125 fl. oz. liquid per day for men and 91 fl. oz. liquid per day for women.
Pricing and Availability
Jack3d Advanced Formula is listed on UPSLabsdirect.com for $19.99 plus free shipping. This is an introductory low price deal.
Is Jack3d Advanced Formula a Great Choice?
Jack3d Advanced Formula contains many scientifically studied ingredients that enhance physical performance. Though, the proprietary blend doesn’t state specific amounts which leave users in the dark as to how much of each ingredient is used. I suggest waiting for user reviews to see how it is received and also to find out more about specific side effects associated with Jack3d Advanced Formula.
However, the introductory price deal the manufacturer is offering is hard to beat. So act fast if you are interested. Who knows how long this deal will last.
 Steven Chen et al. “Arginine and antioxidant supplement on performance in elderly male cyclists: a randomized controlled trial.” J Int Soc Sports Nutr. 2010, 7:13. doi:10.1186/1550-2783-7-13. Available from: http://www.jissn.com/content/7/1/13
 Lundberg JO, Weitzberg E, Gladwin MT. “The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics.” Nat Rev Drug Discov. 2008 Feb;7(2):156-67. Doi: 10.1038/nrd2466. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18167491
 Jon YeanSub Lim. “Effects of Creatine Supplementation on Body Compositon, Strength, and Power of Female Volleyball Players.” Abstract. United States Sports Academy. The Sport Journal. Available from: http://www.thesportjournal.org/article/effects-creatine-supplementation-body-composition
 “Yohimbine (Oral Route).” Mayo Clinic. Available from: http://www.mayoclinic.com/health/drug-information/DR601453
Woolf K, Bidwell WK, Carlson AG. “The effect of caffeine as an ergogenic aid in anaerobic exercise.” Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):412-29. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18708685
 Vinciguerra G et al. “Cramps and muscular pain: prevention with pycnogenol in normal subjects, venous patients, athletes, claudicants and in diabetic microangiopathy.” Angiology. 2006 May-Jun;57(3):331-9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16703193
 Suzuki Y, Ito O, Mukai N, Takahashi H, Takamatsu K. “High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting.” Jpn J Physiol. 2002 Apr;52(2):199-205. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12139778
 “Caffeine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-979-CAFFEINE.aspx?activeIngredientId=979&activeIngredientName=CAFFEINE
 ”Yohimbe.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-759-YOHIMBE.aspx?activeIngredientId=759&activeIngredientName=YOHIMBE
 “Arginine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-875-arginine.aspx?activeIngredientId=875&activeIngredientName=arginine&source=1
 “Creatine.” WebMD Available from: http://www.webmd.com/vitamins-supplements/ingredientmono-873-creatine.aspx?activeIngredientId=873&activeIngredientName=creatine&source=1